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Prof. Malik Peiris

Professor HKU School of Public Health, Hong Kong


Peiris photo Semi formal  
Professor Malik Peiris is a clinical and public health virologist with a particular interest
in emerging virus disease using a “One Health” approach. His research encompasses
the pathogenesis, transmission and ecology of human and animal influenza viruses.
He provided understanding on the emergence and pathogenesis of the 2009 pandemic
H1N1 virus and on avian influenza viruses H5N1, H9N2 and H7N9 and provided
evidence-based options for control of avian viruses in poultry.
In 2003, he discovered a novel coronavirus was the cause of SARS.
Currently he is researching the recently emerged MERS coronavirus.      

Selected Publications  (Pub Med Search)

Chu DKW, Hui KPY, Perera RAPM, Miguel E, Niemeyer D, Zhao J, Channappanavar R, Dudas G, Oladipo JO, Traoré A, Fassi-Fihri O, Ali A, Demissié GF, Muth D, Chan MCW, Nicholls JM, Meyerholz DK, Kuranga SA, Mamo G, Zhou Z, So RTY, Hemida MG, Webby RJ, Roger F, Rambaut A, Poon LLM, Perlman S, Drosten C, Chevalier V, Peiris M. MERS coronaviruses from camels in Africa exhibit region-dependent genetic diversity. Proc Natl Acad Sci U S A. 2018; 115: 3144-3149. (Impact factor 9.7; citations 5)

Ke C, Mok CKP, Zhu W, Zhou H, He J, Guan W, Wu J, Song W, Wang D, Liu J, Lin Q, Chu DKW, Yang L, Zhong N, Yang Z, Shu Y, Peiris JSM. Human Infection with Highly Pathogenic Avian Influenza A(H7N9) Virus, China. Emerg Infect Dis. 2017l;23:1332-1340 (Impact Factor 7.4; citations 45).

Chan MC, Kuok DI, Leung CY, Hui KP, Valkenburg SA, Lau EH, Nicholls JM, Fang X, Guan Y, Lee JW, Chan RW, Webster RG, Matthay MA, Peiris JSM*. Human mesenchymal  stromal cells reduce influenza A H5N1-associated acute lung injury in vitro and in vivo. Proc Natl Acad Sci U S A. 2016;113: 3621-6. (Impact Factor 9.7; citations 22).

Chan RW, Hemida MG, Kayali G, Chu DK, Poon LL, Alnaeem A, Ali MA, Tao KP, Ng HY, Chan MC, Guan Y, Nicholls JM, Peiris JSM*. Tropism and replication of Middle East respiratory syndrome coronavirus from dromedary camels in the human respiratory tract: an in-vitro and ex-vivo study. Lancet Respir Med. 2014;2:813-22. (Impact factor 19.3; citations 31)

Vijaykrishna D, Smith GDJ,  Pybus OG, Zhu H, Bhatt S, Poon LLM, Riley S, Bahl J, Ma SK, Cheung CL, Perera RAPM,  Chen H, Shortridge KF, Webby RJ, Webster RG, Guan Y*, Peiris JSM*. Long-term evolution and transmission dynamics of swine influenza A virus. Nature 2011; 473: 519-22 (Impact factor 40.1; citations 124)

Cowling BJ, Chan KH, Fang VJ, Lau LLH, So THC, Fung ROP Ma ESK, Kwong ASK Chan CW, Tsui WWS, Ngai HY, Chu DWS, Lee PWY, Chiu MC, Leung GM, Peiris JSM. Comparative Epidemiology of Pandemic and Seasonal Influenza A in Households. New Engl J Med 2010; 363: 2175-84. (Impact factor 72.4; citations 223)

Vijaykrishna D, Poon LLM, Zhu HC, Ma SK, Li OTW, Cheung CL, Smith GLD,Peiris JSM*, Guan Y*. Reassortment of pandemic H1N1/2009 influenza A virus in swine. Science 2010; 328: 1529 (Impact factor 37.2; citations 237)

Smith GJ, Vijaykrishna D, Bahl J, Lycett SJ, Worobey M, Pybus OG, Ma SK, Cheung CL, Raghwani J, Bhatt S, Peiris JSM, Guan Y, Rambaut A. Origins and evolutionary genomics of the 2009 swine-origin H1N1 influenza A epidemic. Nature. 2009;459:1122-5 (Impact Factor 40.1; citations 1172).

Nicholls JM, Chan MC, Chan WY, Wong HK, Cheung CY, Kwong DL, Wong MP, Chui WH, Poon LL, Tsao SW, Guan Y, Peiris JSM*. Tropism of avian influenza A (H5N1) in the upper and lower respiratory tract. Nat Med. 2007; 13: 147-9 (Impact factor 29.9; citations 236)

Peiris JSM, de Jong MD, Guan Y. Avian influenza virus (H5N1): a threat to human health. Clin Microbiol Rev. 2007;20:243-67. Review. (Impact Factor 16.2; citations 501)

Li KS, Guan Y, Wang J, Smith GJ, Xu KM, Duan L, Rahardjo AP, Puthavathana P, Buranathai C, Nguyen TD, Estoepangestie AT, Chaisingh A, Auewarakul P, Long HT, Hanh NT, Webby RJ, Poon LL, Chen H, Shortridge KF, Yuen KY, Webster RG, Peiris JSM. Genesis of a highly pathogenic and potentially pandemic H5N1 influenza virus in eastern Asia. Nature. 2004;430:209-13. (Impact factor 40.1; citations 889)

Peiris JSM*, Lai ST, Poon LL, Guan Y, Yam LY, Lim W, Nicholls J, Yee WK, Yan WW, Cheung MT, Cheng VC, Chan KH, Tsang DN, Yung RW, Ng TK, Yuen KY.  Coronavirus as a possible cause of severe acute respiratory syndrome. 2003 361:1319-25 (Impact factor 47.8; citations 1406)

Peiris JSM, Chu CM, Cheng VCC, Chan KS, Hung IFN, Poon LLM, Law KI, Tang BSF, Hon TYW, Chan CS, Chan KH, Ng JSC, Zheng BJ, Ng WL, Lai RWM, Guan Y, Yuen KY. Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study.  2003; 361: 1767-72. (Impact factor 47.8; citations 814)

Cheung CY, Poon LL, Lau AS, Luk W, Lau YL, Shortridge KF, Gordon S, Guan Y, Peiris JSM*. Induction of proinflammatory cytokines in human macrophages by influenza A (H5N1) viruses: a mechanism for the unusual severity of human disease? 2002; 360: 1831-7  (Impact factor 47.8; citations 589)